Browsing by Subject "Transcriptional Activation"
Now showing items 1-3 of 3
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Article
Beyond the histone tail: acetylation at the nucleosome dyad commands transcription.
(2013)Post-translational modifications (PTMs) of histones have been implicated in cellular processes such as transcription, replication and DNA repair. These processes normally involve dynamic changes in chromatin structure and ...
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Article
Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity
(2016)Changes in histone modifications are an attractive model through which environmental signals, such as diet, could be integrated in the cell for regulating its lifespan. However, evidence linking dietary interventions with ...
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Article
Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis
(2006)Notch is the receptor in a signalling pathway that operates in a diverse spectrum of developmental processes. Its ligands (e.g. Serrate) are transmembrane proteins whose signalling competence is regulated by the ...